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Product Name
TSPAN6 antibody
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Description
TSPAN6 Rabbit Polyclonal antibody. Positive WB detected in mouse colon tissue. Observed molecular weight by Western-blot: 25-30kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
A15 homolog antibody; T245 antibody; T245 protein antibody; tetraspanin 6 antibody; Tetraspanin TM4 D antibody; TM4SF6 antibody; TSPAN 6 antibody; TSPAN6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TSPAN6 recombinant protein (Accession Number: NM_003270). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
mouse colon tissue were subjected to SDS PAGE followed by western blot with Catalog No:116364(TSPAN6 antibody) at dilution of 1:1000
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Background
TSPAN6 (also known as TM4SF6) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN6 gene is widely expressed, with high mRNA levels in liver, pancreas, kidney, and ovary (PMID: 9782095). TSPAN6 has been reported as a negative regulator of the RLR pathway by interacting with MAVS in a ubiquitination-dependent manner (PMID: 22908223).
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