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Product Name
TSPAN2 antibody
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Description
TSPAN2 Rabbit Polyclonal antibody. Positive IP detected in HL-60 cells. Positive WB detected in HL-60 cells. Observed molecular weight by Western-blot: 30-35 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human, Mouse, Rat; other species not tested.
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Alternative names
6330415F13Rik antibody; FLJ12082 antibody; NET3 antibody; Tetraspan NET 3 antibody; tetraspanin 2 antibody; TSN2 antibody; TSPAN 2 antibody; TSPAN2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TSPAN2 recombinant protein (Accession Number: NM_005725). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
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Validations
HL-60 cells were subjected to SDS PAGE followed by western blot with Catalog No:116447(TSPAN2 antibody) at dilution of 1:500
IP Result of anti-TSPAN2 (IP:Catalog No:116447, 4ug; Detection:Catalog No:116447 1:500) with HL-60 cells lysate 960ug.
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Background
TSPAN2 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. It has been reported that TSPAN2 is involved in cell invasion and motility during lung cancer progression (PMID: 24726368). TSPAN2 enhances cell motility and invasiveness by assisting CD44 in scavenging intracellular reactive oxygen species.
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