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Product Name
TRPS1 antibody
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Description
TRPS1 Rabbit Polyclonal antibody. Positive IP detected in HeLa cells. Positive WB detected in mouse brain tissue, mouse kidney tissue, rat brain tissue. Positive IF detected in HepG2 cells. Positive IHC detected in human prostate cancer tissue, human kidney tissue. Observed molecular weight by Western-blot: 135-142kd
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Tested applications
ELISA, WB, IF, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
GC79 antibody; LGCR antibody; TRPS1 antibody; Zinc finger protein GC79 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_014112). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: N/AIHC: 1:20-1:200
IF: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116414(TRPS1 antibody) at dilution of 1:100
IP result of anti-TRPS1(Catalog No:116414 for IP and Detection).
Immunohistochemistry of paraffin-embedded human prostate cancer slide using Catalog No:116414(TRPS1 Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human prostate cancer slide using Catalog No:116414(TRPS1 Antibody) at dilution of 1:50
Immunofluorescent analysis of HepG2 cells, using TRPS1 antibody Catalog No:116414 at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
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Background
TRPS1, also named as GC79 and LGCR, is a transcriptional repressor. TRPS1 may act to restrict expression of GATA-regulated genes at selected sites and stages in vertebrate development. It might be involved in prostate cancer apoptosis. Defects in TRPS1 are the cause of tricho-rhino-phalangeal syndrome type 1/2/3 (TRPS1) (TRPS2) (TRPS3). The antbody recognizes the C-term of TRPS1.
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References
- Kuzynski M, Goss M, Bottini M. Dual role of the Trps1 transcription factor in dentin mineralization. The Journal of biological chemistry. 289(40):27481-93. 2014.
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