TRPC1 Polyclonal Antibody

Cat.#: 166254

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Product Information

  • Product Name
    TRPC1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to TRPC1
  • Tested applications
    WB, IHC
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    TRPC1 antibody; HTRP-1 antibody; TRP1 antibody; short transient receptor potential channel 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human TRPC1 (NP_001238774.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IHC 1:50 - 1:200
  • Validations

    Western blot - TRPC1 Polyclonal Antibody

    Western blot - TRPC1 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using TRPC1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 30s.

    Immunohistochemistry - TRPC1 Polyclonal Antibody

    Immunohistochemistry - TRPC1 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded mouse heart using TRPC1 antibody (40x lens).

    Immunohistochemistry - TRPC1 Polyclonal Antibody

    Immunohistochemistry - TRPC1 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded rat brain using TRPC1 antibody (40x lens).

    Immunohistochemistry - TRPC1 Polyclonal Antibody

    Immunohistochemistry - TRPC1 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded rat heart using TRPC1 antibody (40x lens).

  • Background
    Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"