TRPA1 antibody

Cat.#: 116404

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Product Information

  • Product Name
    TRPA1 antibody
  • Documents
  • Description
    TRPA1 Rabbit Polyclonal antibody. Positive WB detected in SH-SY5Y cells. Observed molecular weight by Western-blot: 120-130kd
  • Tested applications
    ELISA, WB
  • Species reactivity
    human; other species not tested.
  • Alternative names
    TRPA1 antibody; ANKTM1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_007332). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

  • Validations

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:116404(TRPA1 antibody) at dilution of 1:500

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:116404(TRPA1 antibody) at dilution of 1:500

  • Background
    TRPA1, also named as ANKTM1, belongs to the transient receptor family. TRPA1 is a receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function. TRPA1 has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes. It acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana. It may be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"