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TRIP13 antibody

Cat.#: 116327

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Product Information

  • Product Name
    TRIP13 antibody
  • Documents
  • Description
    TRIP13 Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, HT-1080 cells, human testis tissue, mouse testis tissue. Positive IP detected in mouse testis tissue. Observed molecular weight by Western-blot: 49 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    16E1 BP antibody; 16E1BP antibody; PCH2 antibody; TR interacting protein 13 antibody; TRIP 13 antibody; TRIP13 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TRIP13 recombinant protein (Accession Number: XM_011514163). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:1000

  • Validations

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:116327(TRIP13 antibody) at dilution of 1:400

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:116327(TRIP13 antibody) at dilution of 1:400

    IP Result of anti-TRIP13 (IP:Catalog No:116327, 3ug; Detection:Catalog No:116327 1:400) with mouse testis tissue lysate 6000ug.

    IP Result of anti-TRIP13 (IP:Catalog No:116327, 3ug; Detection:Catalog No:116327 1:400) with mouse testis tissue lysate 6000ug.

  • Background
    TRIP13 gene encodes thyroid receptor-interacting protein 13, that interact with thyroid hormone receptors, also known as human papillomavirus type 16 E1 protein-binding protein (16E1BP). This protein belongs to the AAA ATPase family and the PCH2 subfamily. TRIP13 gene may be one of the several playing roles in early-stage non-small cell lung cancer. TRIP13 also functions in chromosome recombination and chromosome structure development during meiosis, and it is required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation.
  • References
    • Banerjee R, Russo N, Liu M. TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer. Nature communications. 5:4527. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"