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Product Name
TRIM44 antibody
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Description
TRIM44 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, human liver tissue. Positive IHC detected in human gliomas. Observed molecular weight by Western-blot: 50-55kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
TRIM44 antibody; tripartite motif containing 44 antibody; Protein DIPB antibody; MC7 antibody; HSA249128 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TRIM44 recombinant protein (Accession Number: NM_017583). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:116317(TRIM44 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human gliomas using Catalog No:116317(TRIM44 antibody) at dilution of 1:50 (under 10x lens)
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Background
TRIM44 is one of the family member of TRIM protein, which contains an N-terminal ubiquitin hydrolase-type zinc-finger domain, followed by a coiled-coil domain, a zinc-finger B-box homology domain, and a second coiled-coil domain near the C-terminus. Members of the TRIM protein family are involved in various cellular processes, such as cell proliferation, oncogenesis and antiviral defense. This is a rabbit polyantibody raised against full length of human TRIM44.
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References
- Kashimoto K, Komatsu S, Ichikawa D. Overexpression of TRIM44 contributes to malignant outcome in gastric carcinoma. Cancer science. 103(11):2021-6. 2012.
- Luo Q, Lin H, Ye X, Huang J, Lu S, Xu L. Trim44 facilitates the migration and invasion of human lung cancer cells via the NF-κB signaling pathway. International journal of clinical oncology. 20(3):508-17. 2015.
- Peters CJ, Rees JR, Hardwick RH. A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia. Gastroenterology. 139(6):1995-2004.e15. 2010.
- Yang B, Wang J, Wang Y. Novel function of Trim44 promotes an antiviral response by stabilizing VISA. Journal of immunology (Baltimore, Md. : 1950). 190(7):3613-9. 2013.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"