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Product Name
TRIM15 antibody
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Description
TRIM15 Rabbit Polyclonal antibody. Positive IF detected in Hela cells. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 52kd
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Tested applications
ELISA, WB, IF
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
RING finger protein 93 antibody; RNF93 antibody; TRIM15 antibody; tripartite motif containing 15 antibody; Zinc finger protein 178 antibody; Zinc finger protein B7 antibody; ZNF178 antibody; ZNFB7 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TRIM15 recombinant protein (Accession Number: NM_033229). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IF: 1:10-1:100
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:116299(TRIM15 antibody) at dilution of 1:500
Immunofluorescent analysis of Hela cells, using TRIM15 antibody Catalog No:116299 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
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Background
TRIM15(Tripartite motif-containing protein 15) is also named as RNF93, ZNF178, ZNFB7 and belongs to the TRIM/RBCC family. It acts as an ubiquitin-protein ligase and contributs to the endogenous restriction of retroviruses in cells. This protein has 2 isoforms produced by alternative splicing.
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References
- Uchil PD, Hinz A, Siegel S. TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. Journal of virology. 87(1):257-72. 2013.
- Uchil PD, Pawliczek T, Reynolds TD. TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly. Journal of cell science. 127(Pt 18):3928-42. 2014.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"