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Product Name
TRIM11 antibody
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Description
TRIM11 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, Jurkat cells, K-562 cells. Positive IHC detected in human ovary tumor tissue. Observed molecular weight by Western-blot: 53 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
BIA1 antibody; Protein BIA1 antibody; RING finger protein 92 antibody; RNF92 antibody; TRIM11 antibody; tripartite motif containing 11 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TRIM11 recombinant protein (Accession Number: BC011629). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:116297(TRIM11 antibody) at dilution of 1:100
Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:116297(TRIM11 antibody) at dilution of 1:100 (under 10x lens)
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Background
TRIM11(Tripartite motif-containing protein 11) is also named as RNF92 and Belongs to the TRIM/RBCC family. It is a member of the tripartite-motif-containing protein family and is known to destabilize humanin, an inhibitor of Alzheimer-like neuronal insults(PMID: 16904669). This protein has 3 isoforms produced by alternative splicing.
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References
- Di K, Linskey ME, Bota DA. TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth. Oncogene. 32(42):5038-47. 2013.
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