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Product Name
Mouse TREM-2/TREM2 (His Tag) recombinant protein
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Description
May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
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Protein name
Triggering receptor expressed on myeloid cells 2
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Protein short names
TREM-2; TREM2B; TREM2C; TREM2A
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Uniprot ID
Q99NH8
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Gene Name
Trem2; Trem2a; Trem2b; Trem2c
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse TREM2 (NP_112544.1) extracellular domain (Met 1-Pro 168) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse TREM2 consists of 161 amino acids with the predicted molecular mass of 18 kDa. As a result of glycosylation, the apparent molecular mass of rmTREM2 is approximately 30-40 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Mouse TREM2 Protein (His Tag) SDS-PAGE
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