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Product Name
TRIB2 antibody
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Description
TRIB2 Rabbit Polyclonal antibody. Positive IHC detected in human placenta. Positive WB detected in HeLa cells, Jurkat cells, K-562 cells, mouse thymus tissue. Observed molecular weight by Western-blot: 46kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
TRIB2 antibody; TRB2 antibody; Tribbles homolog 2 antibody; C5FW antibody; TRB 2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TRIB2 recombinant protein (Accession Number: NM_021643). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:116295(TRIB2 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human placenta using Catalog No:116295(TRIB2 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human placenta using Catalog No:116295(TRIB2 antibody) at dilution of 1:50 (under 40x lens)
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Background
TRIB2, also named as TRB2 , belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and Tribbles subfamily. TRIB2 interacts with MAPK kinases and regulates activation of MAP kinases. It does not display kinase activity Antibodies against TRIB2 are present in sera from patients with autoimmune uveitis. TRIB2 is enriched in hypocretin neurons. Sera from narcolepsy patients with cataplexy had higher Trib2-specific antibody titers compared with either normal controls or patients with idiopathic hypersomnia, multiple sclerosis, or other inflammatory neurological disorders.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"