-
Product Name
TREX1 antibody
- Documents
-
Description
TREX1 Rabbit Polyclonal antibody. Positive IP detected in HeLa cells. Positive WB detected in HeLa cells, HepG2 cells. Observed molecular weight by Western-blot: 32 kDa
-
Tested applications
ELISA, WB, IP
-
Species reactivity
Human; other species not tested.
-
Alternative names
3 5 exonuclease TREX1 antibody; AGS1 antibody; AGS5 antibody; CRV antibody; DKFZp434J0310 antibody; DNase III antibody; DRN3 antibody; HERNS antibody; TREX1 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of TREX1 recombinant protein (Accession Number: NM_016381). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:1000
-
Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:116359(TREX1 Antibody) at dilution of 1:300
HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:116359(TREX1 Antibody) at dilution of 1:300
IP Result of anti-TREX1 (IP:Catalog No:116359, 4ug; Detection:Catalog No:116359 1:300) with HeLa cells lysate 1200ug.
-
Background
TREX1 (three prime repair exonuclease 1), also known as trophoblast expressed 1, CRV, AGS1, AGS5, DRN3, HERNS or DNase III, is a member of the exonuclease superfamily and belongs to the TREX family. TREX1 may play a role in DNA repair. TREX1 is expressed in thymus, spleen, liver, brain, heart, small intestine and colon. Mutations or defects in the gene encoding TREX1 have been associated with a variety of diseases, including systemic lupus erythematosus, chilblain lupus (CHBL), Aicardi-Goutieres syndrome type 1 (AGS1) and type 5 (AGS5).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"