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TRAPA/SSR1 antibody

Cat.#: 116339

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Product Information

  • Product Name
    TRAPA/SSR1 antibody
  • Documents
  • Description
    TRAPA/SSR1 Rabbit Polyclonal antibody. Positive WB detected in human liver tissue. Positive IHC detected in human ovary tumor tissue. Observed molecular weight by Western-blot: 34kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    DKFZp781N23103 antibody; FLJ14232 antibody; FLJ22100 antibody; FLJ23034 antibody; FLJ78242 antibody; FLJ93042 antibody; SSR alpha antibody; SSR1 antibody; TRAP alpha antibody; TRAPA antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TRAPA/SSR1 recombinant protein (Accession Number: NM_003144). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IHC: 1:20-1:200

  • Validations

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:116339(TRAPA, SSR1 antibody) at dilution of 1:250

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:116339(TRAPA, SSR1 antibody) at dilution of 1:250

    Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:116339(TRAPA, SSR1 antibody) at dilution of 1:100 (under 25x lens)

    Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:116339(TRAPA, SSR1 antibody) at dilution of 1:100 (under 25x lens)

  • Background
    TRAPA (translocon-associated protein subunit alpha), also known as SSR1 (signal sequence receptor subunit alpha), is a 34-kDa single-spanning membrane glycoprotein of the endoplasmic reticulum (ER) (PMID: 8050590). It is a part of the tetrameric TRAP complex (TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma) which functions in regulating the retention of ER resident proteins (PMID: 7916687). The TRAP complex is also involved in endoplasmic reticulum-associated degradation (ERAD) (PMID: 17380188).
  • References
    • Kaakinen M, Papponen H, Metsikkö K. Microdomains of endoplasmic reticulum within the sarcoplasmic reticulum of skeletal myofibers. Experimental cell research. 314(2):237-45. 2008.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"