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  • Mouse Transferrin Receptor/TFRC/CD71 (His Tag) recombinant protein

Mouse Transferrin Receptor/TFRC/CD71 (His Tag) recombinant protein

Cat.#: 501388

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Product Information

  • Product Name
    Mouse Transferrin Receptor/TFRC/CD71 (His Tag) recombinant protein
  • Documents
  • Description
    Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity).
  • Protein name
    Transferrin receptor protein 1
  • Protein short names
    TFR1; 2610028K12RIK; T9; AI195355; TFRC; TR; TRFR; MTVR1; AI426448; E430033M20RIK; MTVR-1; CD71; P90; AU015758; TRANSFERRIN RECEPTOR; TFR
  • Uniprot ID
    Q62351
  • Gene Name
    Tfrc; Trfr
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain of mouse TFRC (Q62351) (Cys 89-Phe 763) was fused with a polyhistidine tag at the N-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse TFRC comprises 694 amino acids and predicts a molecular mass of 78.3 kDa. The apparent molecular mass of mouse TFRC is approximately 80 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 92 % as determined by SDS-PAGE
  • Validations

    Mouse Transferrin Receptor / TFRC / CD71 Protein (His Tag) SDS-PAGE

    Mouse Transferrin Receptor / TFRC / CD71 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"