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Product Name
transcription termination factor-Specific antibody
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Description
transcription termination factor-Specific Mouse Monoclonal antibody. Positive WB detected in Hela cell. Observed molecular weight by Western-blot: 106 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse; other species not tested.
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Alternative names
TTF 1 antibody; TTF I antibody; TTF1 antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_007344). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107637(TTF1-Specific antibody) at dilution of 1:2000
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Background
TTF1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. It plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5, TTF1 recovers DNA-binding activity. The antibody is specific to TTF1.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"