-
Product Name
TPI1 antibody
- Documents
-
Description
TPI1 Mouse Monoclonal antibody. Positive WB detected in HEK-293 cells, HeLa cells. Observed molecular weight by Western-blot: 27kd
-
Tested applications
ELISA, WB
-
Species reactivity
Human; other species not tested.
-
Alternative names
TIM antibody; TPI antibody; TPI1 antibody; Triose phosphate isomerase antibody; Triosephosphate isomerase antibody; triosephosphate isomerase 1 antibody
-
Isotype
Mouse IgG1
-
Preparation
This antibody was obtained by immunization of TPI1 recombinant protein (Accession Number: NM_000365). Purification method: Caprylic Acid/Ammonium Sulfate Precipitation.
-
Clonality
Monoclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
-
Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107633(TPI1 antibody) at dilution of 1:500
-
Background
TPI1(Triosephosphate isomerase) is also named as TIM, TPI and belongs to the triosephosphate isomerase family. It is a key enzyme in cell metabolism that controls the glycolytic flow and energy production through the interconversion of dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde 3-phosphate (G3P)(PMID:19251756). Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency). It can exsit as a homodimer(PMID:18562316).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"