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Product Name
TP63 antibody
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Description
TP63 Mouse Monoclonal antibody. Positive WB detected in PC-3 cells. Observed molecular weight by Western-blot: 68 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
AIS antibody; B(p51A) antibody; B(p51B) antibody; CUSP antibody; EEC3 antibody; KET antibody; LMS antibody; NBP antibody; OFC8 antibody; p40 antibody; p51 antibody; p53CP antibody; p63 antibody; p73H antibody; p73L antibody; RHS antibody; SHFM4 antibody; TP53CP antibody; TP53L antibody; TP63 antibody; TP73L antibody; Tumor protein 63 antibody; tumor protein p63 antibody; Tumor protein p73 like antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of TP63 recombinant protein (Accession Number: NM_003722). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:107632(TP63 Antibody) at dilution of 1:1000
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Background
TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40), 50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.
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