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Product Name
Mouse TLR2/CD282 (His Tag) recombinant protein
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Description
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins (By similarity).
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Protein name
Toll-like receptor 2
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Protein short names
CD282; LY105; TIL4; TOLL/INTERLEUKIN 1 RECEPTOR-LIKE 4; TOLL/INTERLEUKIN-1 RECEPTOR-LIKE PROTEIN 4
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Uniprot ID
Q9QUN7
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Gene Name
Tlr2
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse TLR2 (Q9QUN7) (Met1-Gln587) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse TLR2 consists of 573 amino acids and has a calculated molecular mass of 64.8 kDa. The recombinant protein migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Mouse TLR2 Protein (His Tag) SDS-PAGE
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"