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TNFSF13 antibody

Cat.#: 116293

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Product Information

  • Product Name
    TNFSF13 antibody
  • Documents
  • Description
    TNFSF13 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, Raji cells, SH-SY5Y cells. Positive IF detected in SH-SY5Y cells. Observed molecular weight by Western-blot: 32 kDa
  • Tested applications
    ELISA, WB, IF
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    APRIL antibody; CD256 antibody; ligand antibody; TALL 2 antibody; TALL2 antibody; TNF related death ligand 1 antibody; TNFSF13 antibody; TRDL 1 antibody; UNQ383/PRO715 antibody; ZTNF2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TNFSF13 recombinant protein (Accession Number: NM_172088). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IF: 1:10-1:100

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116293(APRIL,TNFSF13 antibody) at dilution of 1:300

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116293(APRIL,TNFSF13 antibody) at dilution of 1:300

    Immunofluorescent analysis of SH-SY5Y cells using Catalog No:116293(APRIL,TNFSF13 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

    Immunofluorescent analysis of SH-SY5Y cells using Catalog No:116293(APRIL,TNFSF13 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Background
    TNFSF13 gene encodes tumor necrosis factor ligand superfamily member 13 (or APRIL) belonging to the tumor necrosis factor (TNF) family. APRIL is highly expressed in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages, and its precursor is cleaved by furin. APRIL may be implicated in the regulation of tumor cell growth and also monocyte/macrophage-mediated immunological processes.
  • References
    • Ding W, Wang J, Sun B. APRIL knockdown suppresses migration and invasion of human colon carcinoma cells. Clinical biochemistry. 42(16-17):1694-8. 2009.
    • Ding W, Ju S, Jiang S, Zhu L, Wang Y, Wang H. Reduced APRIL expression induces cellular senescence via a HSPG-dependent pathway. Pathology oncology research : POR. 15(4):693-701. 2009.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"