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Product Name
TNFRSF10C Polyclonal Antibody
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Description
Polyclonal antibody to TNFRSF10C
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
TNFRSF10C antibody; CD263 antibody; DCR1 antibody; DCR1-TNFR antibody; LIT antibody; TRAIL-R3 antibody; TRAILR3 antibody; TRID antibody; TNF receptor superfamily member 10c antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-130 of human TNFRSF10C (NP_003832.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - TNFRSF10C Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using TNFRSF10C antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 10s.
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Background
Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"