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Product Name
TMEM208 antibody
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Description
TMEM208 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Observed molecular weight by Western-blot: 19-29 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
HSPC171 antibody; TMEM208 antibody; transmembrane protein 208 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TMEM208 recombinant protein (Accession Number: NM_014187). Purification method: Antigen Affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116176(TMEM208 Antibody) at dilution of 1:300
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Background
Transmembrane protein 208 (TMEM208) can regulate both autophagy and ER stress. When overexpressed, TMEM208 impaired autophagy as characterized by the decrease of the accumulation of LC3-II, decreased degradation of autophagic substrates, and reduced expression of critical effectors and vital molecules of the ER stress and autophagy processes. (PMID: 23691174)
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"