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Product Name
TMC1 antibody
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Description
TMC1 Rabbit Polyclonal antibody. Positive IHC detected in human placenta tissue. Positive WB detected in mouse brain tissue. Observed molecular weight by Western-blot: 88kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
DFNA36 antibody; DFNB11 antibody; DFNB7 antibody; TMC1 antibody; transmembrane channel like 1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_138691). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116081(TMC1 antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human placenta using Catalog No:116081(TMC1 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human placenta using Catalog No:116081(TMC1 antibody) at dilution of 1:100 (under 40x lens)
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Background
TMC1 belongs to the TMC family. It is required for the normal function of cochlear hair cells. Defects in TMC1 are the cause of deafness autosomal dominant type 36 (DFNA36). Defects in TMC1 are the cause of deafness autosomal recessive type 7 (DFNB7). The antibody is specific to TMC1.
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