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Product Name
Human Thyroid peroxidase / TPO (257 Ser/Ala, 725 Pro/Thr, His Tag) recombinant protein
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Description
Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
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Protein name
Thyroid peroxidase
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Protein short names
THYROID MICROSOMAL ANTIGEN; MSA; THYROPEROXIDASE; TPX; TDH2A
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Uniprot ID
P07202
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Gene Name
TPO
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human TPO (P07202-1) extracellular domain (Met 1-Arg846, 257 Ser/Ala, 725 Pro/Thr) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human TPO comprises 842 amino acids and has a predicted molecular mass of 93.8 kDa. The apparent molecular mass of rh TPO (1-846) is approximately 90-100 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human Thyroid peroxidase / TPO Protein (257 Ser/Ala, 725 Pro/Thr, His Tag) SDS-PAGE
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