Thyroglobulin antibody

Thyroglobulin antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Thyroglobulin Mouse Monoclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IHC detected in human thyroid tissue, human thyroid cancer tissue.

ELISA, WB, IHC

Human; other species not tested.

AITD3 antibody; TGN antibody; thyroglobulin antibody

Mouse IgG2a

This antibody was obtained by immunization of Thyroglobulin recombinant protein (Accession Number: NM_003235). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.