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Product Name
TFEC Polyclonal Antibody
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Description
Polyclonal antibody to TFEC
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Tested applications
WB
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Species reactivity
Human
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Alternative names
TFEC antibody; TCFEC antibody; TFE-C antibody; TFEC-L antibody; TFECL antibody; bHLHe34 antibody; hTFEC-L antibody; transcription factor EC antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic Peptide of human TFEC
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
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Validations
Western blot - TFEC Polyclonal Antibody
Western blot analysis of extracts of MDA-MB231 cells, using TFEC antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"