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TFDP2 antibody

Cat.#: 116007

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Product Information

  • Product Name
    TFDP2 antibody
  • Documents
  • Description
    TFDP2 Rabbit Polyclonal antibody. Positive IP detected in SH-SY5Y cells. Positive WB detected in human brain tissue. Observed molecular weight by Western-blot: 49kd
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    Dp 2 antibody; DP2 antibody; E2F dimerization partner 2 antibody; TFDP2 antibody; Transcription factor Dp 2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TFDP2 recombinant protein (Accession Number: NM_001178138). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:1000

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116007(TFDP2 antibody) at dilution of 1:400

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116007(TFDP2 antibody) at dilution of 1:400

    IP Result of anti-TFDP2 (IP:Catalog No:116007, 4ug; Detection:Catalog No:116007 1:400) with SH-SY5Y cells lysate 1600ug.

    IP Result of anti-TFDP2 (IP:Catalog No:116007, 4ug; Detection:Catalog No:116007 1:400) with SH-SY5Y cells lysate 1600ug.

  • Background
    TFDP2, also known as E2FDP2, is a coactivator of E2F factors and involves in EGF or IFN-gamma-mediated effects by enhancing or reducing active heterodimeric complexes. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis [PMID:16360038]. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication [PMID:16721044].
  • References
    • Caron E, Vincent K, Fortier MH. The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation. Molecular systems biology. 7:533. 2011.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"