TEAD1 antibody

TEAD1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

TEAD1 Rabbit Polyclonal antibody. Positive WB detected in human skeletal muscle tissue. Positive IP detected in mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 52 kDa

ELISA, WB, IP

Human,Mouse,Rat; other species not tested.

NTEF 1 antibody; Protein GT IIC antibody; REF1 antibody; TCF 13 antibody; TCF13 antibody; TEA domain family member 1 antibody; TEAD 1 antibody; TEAD1 antibody; TEF 1 antibody; TEF1 antibody; Transcription factor 13 antibody

Rabbit IgG

This antibody was obtained by immunization of TEAD1 recombinant protein (Accession Number: BC026959). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

TEAD1 belongs to a protein family that share the TEA/ATTS domain. It acts as a transcriptional factor by binding to the GT-IIC and Sph(I 1 II) enhansons in the simian virus 40 (SV40) enhancer. Also it can modulate SV40 late transcription together with large T antigen. The transcriptional activity of TEAD1 required several regions of the proteins , a TBP-associated factors and a limiting transcriptional intermediary facotrs. TEAD1 also preforms an essential role in the Hippo signaling pathway. TEAD1 regulates gene rexpression of YAP1 and WWTR1/TAZ, thus mediating cell proliferation, migration and epithelial mesenchymal transition induction. TEAD is preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart.

• Cao JJ, Zhao XM, Wang DL. YAP is overexpressed in clear cell renal cell carcinoma and its knockdown reduces cell proliferation and induces cell cycle arrest and apoptosis. Oncology reports. 32(4):1594-600. 2014.