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Product Name
TDRD3 antibody
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Description
TDRD3 Rabbit Polyclonal antibody. Positive IP detected in HeLa cells. Positive WB detected in HEK-293 cells. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 73 kDa; 83 kDa
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Tested applications
ELISA, WB, IP, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FLJ21007 antibody; TDRD3 antibody; tudor domain containing 3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TDRD3 recombinant protein (Accession Number: NM_030794). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
IF: 1:10-1:100
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:115928(TDRD3 antibody) at dilution of 1:300
IP Result of anti-TDRD3 (IP:Catalog No:115928, 3ug; Detection:Catalog No:115928 1:1000) with HeLa cells lysate 3800ug.
Immunofluorescent analysis of HeLa cells using Catalog No:115928(TDRD3 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
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Background
TDRD3 (Tudor domain-containing protein 3) contains tudor domain which is an approximately 60-amino acid structure motif. TDRD3 functions as a scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. TDRD3 is a transcriptional coactivator that promotes transcription by binding methylarginine marks on histone tails. TDRD3 also possesses an oligosaccharide/nucleotide binding fold and an ubiquitin associated domain capable of binding tetra-ubiquitin, and it is reported to associate with polyribosomes in HeLa cells.
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