TCEAL7 antibody

Cat.#: 115899

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Product Information

  • Product Name
    TCEAL7 antibody
  • Documents
  • Description
    TCEAL7 Rabbit Polyclonal antibody. Positive WB detected in human liver tissue, A549 cells. Positive IHC detected in human ovary tumor. Observed molecular weight by Western-blot: 12 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    human; other species not tested.
  • Alternative names
    TCEAL7 antibody; TCEA like protein 7 antibody; MPMGp800C04260Q003 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TCEAL7 recombinant protein (Accession Number: NM_152278). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:115899(TCEAL7 antibody) at dilution of 1:500

    human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:115899(TCEAL7 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:115899(TCEAL7 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:115899(TCEAL7 antibody) at dilution of 1:50 (under 40x lens)

  • Background
    TCEAL7 is a transcription regulatory factor that has a role in the negative regulation of NF-kappa-B signaling at the basal level by regulating transcriptional activity of NF-kappa-B on its target gene promoters. It can associate with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. In addition, TCEAL7 regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines
  • References
    • Huang CY, Chen YM, Zhao JJ. Decreased expression of transcription elongation factor A-like 7 is associated with gastric adenocarcinoma prognosis. PloS one. 8(1):e54671. 2013.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"