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Product Name
TBX3 antibody
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Description
TBX3 Rabbit Polyclonal antibody. Positive IP detected in human placenta tissue. Positive WB detected in mouse placenta tissue, HepG2 cells. Observed molecular weight by Western-blot: 80 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
T box 3 antibody; T box protein 3 antibody; TBX3 antibody; TBX3 ISO antibody; UMS antibody; XHL antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TBX3 recombinant protein (Accession Number: NM_016569). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
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Validations
mouse placenta tissue were subjected to SDS PAGE followed by western blot with Catalog No:115892(TBX3 antibody) at dilution of 1:500
IP Result of anti-TBX3 (IP:Catalog No:115892, 4ug; Detection:Catalog No:115892 1:500) with human placenta tissue lysate 1520ug.
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Background
TBX3, also named as T-box protein 3, is a 743 amino acid protein, which contains 1 T-box DNA-binding domain. TBX3 may localize in the nucleus and is widely expressed in various tissues. TBX3 as a transcriptional repressor is involved in developmental processes and probably plays a role in limb pattern formation. TBX3 plays an important role on osteogenic differentiation and proliferation of human mesenchymal stem cell derived from adipose tissue.
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References
- Du HF, Ou LP, Yang X. A new PKCα/β/TBX3/E-cadherin pathway is involved in PLCε-regulated invasion and migration in human bladder cancer cells. Cellular signalling. 26(3):580-93. 2014.
- Lin Z, Zhang Y, Gao T. Homologous recombination efficiency enhanced by inhibition of MEK and GSK3β. Genesis (New York, N.Y. : 2000). 52(11):889-96. 2014.
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