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Product Name
TAZ antibody
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Description
TAZ Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue, human heart tissue, human thyroid cancer tissue. Positive IP detected in MDA-MB-453s cells. Positive WB detected in MDA-MB-453s cells, LN229 cells. Observed molecular weight by Western-blot: 50 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human; other species not tested.
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Alternative names
DKFZp586I1419 antibody; TAZ antibody; WWTR1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TAZ recombinant protein (Accession Number: NM_001168280). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:1000
IHC: 1:20-1:200
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Validations
MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with Catalog No:115860(WWTR1,TAZ Antibody) at dilution of 1:2000
WB result of WWTR1 antibody (TAZ antibody, Catalog No:115860, 1:1000) with LN229 cell lysate by Dr. Xiaobing He. (Lane 1, LN229 (GBM cell line) cell lysate. 90 ug; Lane 2, LN229 growth inhibition treatment. 90 ug)
Immunohistochemistry of paraffin-embedded human breast cancer slide using Catalog No:115860 (TAZ Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human breast cancer slide using Catalog No:115860 (TAZ Antibody) at dilution of 1:50 (under 40x lens)
IP Result of anti-WWTR1,TAZ (IP:Catalog No:115860, 4ug; Detection:Catalog No:115860 1:300) with MDA-MB-453s cells lysate 2800ug.
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Background
WWTR1 represents WW domain containing transcription regulator 1
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References
- Li L, Fang R, Liu B. Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth. Oncogene. 2015.
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