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TAOK2 antibody

Cat.#: 115848

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Product Information

  • Product Name
    TAOK2 antibody
  • Documents
  • Description
    TAOK2 Rabbit Polyclonal antibody. Positive IP detected in HEK-293 cells. Positive WB detected in mouse brain tissue, HEK-293 cells, L02 cells. Observed molecular weight by Western-blot: 138-150 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    hKFC C antibody; KIAA0881 antibody; Kinase from chicken homolog C antibody; MAP3K17 antibody; PSK antibody; PSK 1 antibody; PSK1 antibody; TAO kinase 2 antibody; TAO1 antibody; TAO2 antibody; TAOK2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TAOK2 recombinant protein (Accession Number: NM_016151). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:2000

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115848(TAOK2 antibody) at dilution of 1:300

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115848(TAOK2 antibody) at dilution of 1:300

    IP Result of anti-TAOK2 (IP:Catalog No:115848, 4ug; Detection:Catalog No:115848 1:500) with HEK-293 cells lysate 3000ug.

    IP Result of anti-TAOK2 (IP:Catalog No:115848, 4ug; Detection:Catalog No:115848 1:500) with HEK-293 cells lysate 3000ug.

  • Background
    TAOK2(Serine/threonine-protein kinase TAO2) is also named as KIAA0881, MAP3K17, PSK, PSK1 and belongs to the protein kinase superfamily. TAOK2 is known to modulate gene transcription via its activation of several MAP kinase pathways, including c-Jun amino-terminal kinase (JNK), and has been implicated in the modulation of actin and microtubule dynamics. The time course of TAOK2 expression is consistent with a role for it in neuronal differentiation.(PMID:22735514).
  • References
    • Tavares IA, Touma D, Lynham S. Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease. The Journal of biological chemistry. 288(21):15418-29. 2013.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"