TAF1-Specific antibody

TAF1-Specific antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

TAF1-Specific Rabbit Polyclonal antibody. Positive IHC detected in human brain. Positive WB detected in mouse brain tissue, Jurkat cells. Observed molecular weight by Western-blot: 50kd

ELISA, WB, IHC

human, mouse; other species not tested.

TAF1 antibody; NSCL2 antibody; CCGS antibody; P250 antibody; N TAF1 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_138923). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

TAF1, also named as BA2R, CCG1, CCGS, TAF2A, p250, Cell cycle gene 1 protein, TAFII250 and DYT3, belongs to the TAF1 family. TAF1 is the largest component and core scaffold of the TFIID basal transcription factor complex. It contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. TAF1 phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. TAF1 phosphorylates GTF2A1 and GTF2F1 on Ser residues. It possesses DNA-binding activity. It is essential for progression of the G1 phase of the cell cycle. Defects in TAF1 are the cause of dystonia type 3 (DYT3) which also called X-linked dystonia-parkinsonism (XDP). The antibody is specific to TAF1.