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Product Name
TADA3L antibody
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Description
TADA3L Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, human brain tissue, NIH/3T3 cells. Positive IHC detected in human prostate cancer tissue. Observed molecular weight by Western-blot: 49 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ADA3 antibody; ADA3 homolog antibody; ADA3 like protein antibody; FLJ20221 antibody; FLJ21329 antibody; hADA3 antibody; STAF54 antibody; TADA3 antibody; TADA3L antibody; Transcriptional adapter 3 antibody; Transcriptional adapter 3 like antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TADA3L recombinant protein (Accession Number: NM_133481). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:115976(TADA3L antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:115976(TADA3L antibody) at dilution of 1:100 (under 10x lens)
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Background
TADA3 is a subunit of 2 histone acetyltransferase complexes: the ADA2A (TADA2A)-containing (ATAC) complex and the SPT3 (SUPT3H)-TAF9-GCN5 (KAT2A)/PCAF (KAT2B) acetylase (STAGA) complex. The ATAC complex is a complex with histone acetyltransferase activity on histones H3 and H4, and the PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. TADA3 is also known as a coactivator for p53/TP53-dependent transcriptional activation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"