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TADA2L antibody

Cat.#: 115975

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Product Information

  • Product Name
    TADA2L antibody
  • Documents
  • Description
    TADA2L Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue. Positive IP detected in mouse testis tissue. Positive IHC detected in human colon cancer tissue. Observed molecular weight by Western-blot: 51.5 kDa
  • Tested applications
    ELISA, WB, IHC, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    ADA2 antibody; ADA2 like protein antibody; ADA2A antibody; FLJ12705 antibody; hADA2 antibody; KL04P antibody; TADA2A antibody; TADA2L antibody; Transcriptional adapter 2 like antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TADA2L recombinant protein (Accession Number: NM_001488). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:1000

    IHC: 1:20-1:200

  • Validations

    mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:115975(TADA2L antibody) at dilution of 1:400

    mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:115975(TADA2L antibody) at dilution of 1:400

    Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:115975(TADA2L antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:115975(TADA2L antibody) at dilution of 1:50 (under 10x lens)

    IP Result of anti-TADA2L (IP:Catalog No:115975, 4ug; Detection:Catalog No:115975 1:300) with mouse testis tissue lysate 4000ug.

    IP Result of anti-TADA2L (IP:Catalog No:115975, 4ug; Detection:Catalog No:115975 1:300) with mouse testis tissue lysate 4000ug.

  • Background
    TADA2A is a subunit of the ADA2A-containing (ATAC) histone acetyltransferase complex, which with histone acetyltransferase activity on histones H3 and H4. It is required for the function of some acidic activation domains, which activate transcription from a distant site. It has a role in chromatin remodeling by binding at the linker region between neighbouring unclesomes of dinucleosomes [PMID:19103755].
  • References
    • Guelman S, Kozuka K, Mao Y. The double-histone-acetyltransferase complex ATAC is essential for mammalian development. Molecular and cellular biology. 29(5):1176-88. 2009.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"