TADA2A Polyclonal Antibody

TADA2A Polyclonal Antibody

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• Material Safety Data Sheets (MSDS)

Polyclonal antibody to TADA2A

WB

Human, Mouse, Rat

TADA2A antibody; ADA2 antibody; ADA2A antibody; KL04P antibody; TADA2L antibody; hADA2 antibody; transcriptional adaptor 2A antibody

Rabbit IgG

Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-443 of human TADA2A (NP_001159577.2).

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.

WB 1:500 - 1:2000

Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage.