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Product Name
SYNJ2BP antibody
- Documents
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Description
SYNJ2BP Rabbit Polyclonal antibody. Positive IF detected in MCF-7 cells. Positive IHC detected in human stomach cancer tissue. Positive IP detected in mouse lung tissue. Positive WB detected in human heart tissue, A549 cells, human kidney tissue, mouse lung tissue. Observed molecular weight by Western-blot: 16kd
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Tested applications
ELISA, WB, IHC, IF, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
ARIP2 antibody; FLJ11271 antibody; FLJ41973 antibody; OMP25 antibody; synaptojanin 2 binding protein antibody; SYNJ2BP antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SYNJ2BP recombinant protein (Accession Number: NM_018373). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IP: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:10-1:100
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Validations
human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:115785(ARIP2; SYNJ2BP antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human stomach cancer using Catalog No:115785(ARIP2; SYNJ2BP antibody) at dilution of 1:50 (under 40x lens)
Immunofluorescent analysis of MCF-7 cells, using SYNJ2BP antibody Catalog No:115785 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
IP Result of anti-ARIP2; SYNJ2BP (IP:Catalog No:115785, 3ug; Detection:Catalog No:115785 1:500) with mouse lung tissue lysate 4000ug.
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Background
Activin, a member of the TGF-beta superfamily, plays important roles in reproductive tissues as a stimulator of follicle-stimulating hormone (FSH) secretion and inhibits the proliferation of breast cancer cells. Activin receptor-interacting protein 2 (ARIP2), also known as synaptojanin-2-binding protein (SYNJ2BP), is located in the outer membrane of mitochondria. ARIP2 is widely distributed in various human tissues, and has been recently identified in mouse tissues as a regulatory protein of activin signal transduction by interacting with activin type II receptors. ARIP2 may be a putative growth-promoting factor involved in breast tumorigenesis and tumor development.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"