SUMO4 Polyclonal Antibody

Cat.#: 165412

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Product Information

  • Product Name
    SUMO4 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to SUMO4
  • Tested applications
    WB, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    SUMO4 antibody; IDDM5 antibody; SMT3H4 antibody; SUMO-4 antibody; dJ281H8.4 antibody; small ubiquitin-like modifier 4 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human SUMO4 (NP_001002255.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IF 1:50 - 1:200
  • Validations

    Western blot - SUMO4 Polyclonal Antibody

    Western blot - SUMO4 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using SUMO4 antibody at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit ._Exposure time: 40s.

    Immunofluorescence - SUMO4 Polyclonal Antibody

    Immunofluorescence - SUMO4 Polyclonal Antibody

    Immunofluorescence analysis of A549 cells using SUMO4 antibody . Blue: DAPI for nuclear staining.

  • Background
    Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"