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Product Name
SULT1C2 antibody
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Description
SULT1C2 Rabbit Polyclonal antibody. Positive WB detected in human stomach tissue, human kidney tissue, human liver tissue, mouse liver tissue. Positive IHC detected in human prostate cancer tissue. Observed molecular weight by Western-blot: 30-35kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse, Rat; other species not tested.
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Alternative names
humSULTC2 antibody; ST1C1 antibody; ST1C2 antibody; Sulfotransferase 1C1 antibody; Sulfotransferase 1C2 antibody; SULT1C#1 antibody; SULT1C1 antibody; SULT1C2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SULT1C2 recombinant protein (Accession Number: NM_001056). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
human stomach tissue were subjected to SDS PAGE followed by western blot with Catalog No:115829(SULT1C2 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:115829(SULT1C2 antibody) at dilution of 1:100 (under 25x lens)
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Background
SULT1C2, also named as SULT1C1, ST1C2, ST1C1, and humSULTC2, belongs to the sulfotransferase 1 family. It is a sulfotransferase enzymes that catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. SULT1C2 may be involved in the activation of carcinogenic hyroxylamines. It is responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds.
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References
- Shu XH, Li H, Sun Z. Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells. Biochemical pharmacology. 79(10):1516-25. 2010.
- Shu XH, Li H, Sun XX. Metabolic patterns and biotransformation activities of resveratrol in human glioblastoma cells: relevance with therapeutic efficacies. PloS one. 6(11):e27484. 2011.
- Sun Z, Li H, Shu XH. Distinct sulfonation activities in resveratrol-sensitive and resveratrol-insensitive human glioblastoma cells. The FEBS journal. 279(13):2381-92. 2012.
- Sun Z, Shi S, Li H. Evaluation of resveratrol sensitivities and metabolic patterns in human and rat glioblastoma cells. Cancer chemotherapy and pharmacology. 72(5):965-73. 2013.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"