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Product Name
STXBP1 antibody
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Description
STXBP1 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, mouse brain tissue. Positive IHC detected in human brain. Observed molecular weight by Western-blot: 60kd,67kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
STXBP1 antibody; UNC18A antibody; RBSEC1 antibody; Unc 18A antibody; Protein unc 18 homolog A antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_003165). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115808(STXBP1 antibody) at dilution of 1:800
Immunohistochemical of paraffin-embedded human brain using Catalog No:115808(STXBP1 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human brain using Catalog No:115808(STXBP1 antibody) at dilution of 1:100 (under 40x lens)
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Background
STXBP1, also named as UNC18A, N-Sec1 and p67 belongs to the STXBP/unc-18/SEC1 family. STXBP1 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. STXBP1 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions. The antibody is specific to STXBP1.
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