-
Product Name
STRN antibody
- Documents
-
Description
STRN Rabbit Polyclonal antibody. Positive IF detected in Hela cells. Positive WB detected in mouse brain tissue, A549 cells, mouse cerebellum tissue, NIH/3T3 cells. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 110 kDa
-
Tested applications
ELISA, WB, IF, IP
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
SG2NA antibody; Striatin antibody; STRN antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of STRN recombinant protein (Accession Number: BC106879). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
IF: 1:10-1:100
-
Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115737(STRN antibody) at dilution of 1:500
IP Result of anti-STRN (IP:Catalog No:115737, 4ug; Detection:Catalog No:115737 1:1000) with mouse brain tissue lysate 8000ug.
Immunofluorescent analysis of Hela cells, using STRN antibody Catalog No:115737 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
-
Background
STRN (Striatin), a 780-amino acid protein, was identified and cloned more than a decade ago. In adult mammals, striatin is mainly expressed in neurons of both the central and peripheral nervous systems with very high levels of expression in the striatum, hence its name. STRN-ALK fusion may be a potential therapeutic target in the aggressive forms of thyroid cancer (PMID: 24475247).
-
References
- Chen L, Ma L, Bai Q. Heavy metal-induced metallothionein expression is regulated by specific protein phosphatase 2A complexes. The Journal of biological chemistry. 289(32):22413-26. 2014.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"