STAT5B antibody

STAT5B antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

STAT5B Rabbit Polyclonal antibody. Positive WB detected in K-562 cells. Observed molecular weight by Western-blot: 91kd

ELISA, WB

human; other species not tested.

STAT5B antibody; STAT5B-Specific antibody; STAT5 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_012448). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

STAT5B belongs to the transcription factor STAT family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B carries out a dual function: signal transduction and activation of transcription. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This antibody is specific to STAT5B. It has no cross reaction to STAT5A.