Stanniocalcin 2 antibody

Cat.#: 107605

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Product Information

  • Product Name
    Stanniocalcin 2 antibody
  • Documents
  • Description
    Stanniocalcin 2 Mouse Monoclonal antibody. Positive WB detected in HEK-293 cells. Positive IHC detected in human breast cancer tissue, human kidney tissue, human stomach cancer tissue. Positive IF detected in Hela cells. Observed molecular weight by Western-blot: 33 kDa
  • Tested applications
    ELISA, WB, IF, IHC
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    stanniOCalcin 2 antibody; StanniOCalcin related protein antibody; STC 2 antibody; STC related protein antibody; STC2 antibody; STCRP antibody
  • Isotype
    Mouse IgG1
  • Preparation
    This antibody was obtained by immunization of Stanni℃alcin 2 recombinant protein (Accession Number: NM_003714). Purification method: Caprylic acid/ammonium sulfate precipitation.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

    IF: 1:10-1:100

  • Validations

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107605(STC2 antibody) at dilution of 1:1000

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107605(STC2 antibody) at dilution of 1:1000

    Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:107605(STC2 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:107605(STC2 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:107605(STC2 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:107605(STC2 antibody) at dilution of 1:50 (under 40x lens)

    Immunofluorescent analysis of Hela cells, using STC2 antibody Catalog No: at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

    Immunofluorescent analysis of Hela cells, using STC2 antibody Catalog No: at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

  • Background
    Stanniocalcin (STC) is a family of secreted glycoprotein hormones that originally discovered in the corpuscles of Stannius, an endocrine gland of fish. STC1 and STC2, two homologues of STC family, are reported to involve in calcium and phosphate homeostasis. It is expressed in a wide variety of tissues such as kidney, spleen, heart, and pancreas. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. STC2 overexpression could promote tumor cell proliferation, invasion and metastasis in prostate cancer, ovarian cancer or neuroblastoma. STC2 is also vital for cytoprotective properties when exposed to ER stress and hypoxia.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"