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Product Name
Mouse Osteonectin / SPARC (His Tag) recombinant protein
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Description
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
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Protein name
SPARC
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Protein short names
BM-40; OSTEONECTIN; CYSTEINE-RICH PROTEIN; RP23-465I4.1; ON; SPARC; AA517111
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Uniprot ID
Q5NCU5
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Gene Name
Sparc
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse SPARC (NP_033268.1) (Met 1-Ile 302) was expressed, with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse SPARC consists of 296 amino acids and has a predicted molecular mass of 34 kDa. In SDS-PAGE under reducing conditions, rm SPARC migrates as an approximately 43 kDa band due to glycosylation.
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Purity
> 96 % as determined by SDS-PAGE
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Validations
Mouse Osteonectin / SPARC Protein (His Tag) SDS-PAGE
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