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Sortilin antibody

Cat.#: 115507

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Product Information

  • Product Name
    Sortilin antibody
  • Documents
  • Description
    Sortilin Rabbit Polyclonal antibody. Positive IP detected in rat brain tissue. Positive WB detected in human brain tissue, rat brain tissue. Positive IHC detected in human brain tissue, human lung cancer tissue. Observed molecular weight by Western-blot: 92 kDa
  • Tested applications
    ELISA, WB, IP, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    100 kDa NT receptor antibody; Glycoprotein 95 antibody; Gp95 antibody; Neurotensin receptor 3 antibody; NT3 antibody; NTR3 antibody; SORT1 antibody; Sortilin antibody; sortilin 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Sortilin recombinant protein (Accession Number: NM_002959). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:2000

    IHC: 1:50-1:500

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115507(SORT1 antibody) at dilution of 1:1200

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115507(SORT1 antibody) at dilution of 1:1200

    IP Result of anti-SORT1 (IP:Catalog No:115507, 4ug; Detection:Catalog No:115507 1:500) with rat brain tissue lysate 4000ug.

    IP Result of anti-SORT1 (IP:Catalog No:115507, 4ug; Detection:Catalog No:115507 1:500) with rat brain tissue lysate 4000ug.

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:115507(SORT1 Antibody) at dilution of 1:100 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:115507(SORT1 Antibody) at dilution of 1:100 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:115507(SORT1 Antibody) at dilution of 1:100 (under 40x lens).

    Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:115507(SORT1 Antibody) at dilution of 1:100 (under 40x lens).

  • Background
    Sortilin 1 (SORT1), is a trans-Golgi network (TGN) transmembrane protein and is a member of the Vps10p domain receptor family. SORT1 binds a number of unrelated ligands that participate in a wide range of cellular processes. It functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface.
  • References
    • Wang G, Wu Y, Zhou T. Mapping of the N-linked glycoproteome of human spermatozoa. Journal of proteome research. 12(12):5750-9. 2013.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"