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Product Name
SORCS1 antibody
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Description
SORCS1 Rabbit Polyclonal antibody. Positive FC detected in HeLa cells. Positive IHC detected in human brain tissue. Positive WB detected in mouse brain tissue, HEK-293 cells, human brain tissue, K-562 cells, mouse kidney tissue. Observed molecular weight by Western-blot: 60-80 kDa
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Tested applications
ELISA, WB, IHC, FC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
FLJ41758 antibody; FLJ43475 antibody; FLJ44957 antibody; hSorCS antibody; SORCS antibody; SORCS1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SORCS1 recombinant protein (Accession Number: NM_052918). Purification method: Antigen Affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:115504(SORCS1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:115504(SORCS1 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human brain tissue slide using Catalog No:115504(SORCS1 Antibody) at dilution of 1:50 (under 40x lens)
1X10^6 HeLa cells were stained with 0.2ug SORCS1 antibody (Catalog No:115504, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.
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Background
SORCS1, also named as SorCS, belongs to the family of VPS10 domain-containing receptors. SorCS1 immunoreactivity is widespread in a population of neurons throughout the brain. Two different types of cellular localization were observed. Most SorCS1 immunoreactive neurons exhibit a punctate cytoplasmic staining which extends into the dendrites, whilst occassionally SorCS1 neuronal immunoreactivity is associated with the plasma membrane.
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