Cart 2

SORCS1 antibody

Cat.#: 115503

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    SORCS1 antibody
  • Documents
  • Description
    SORCS1 Rabbit Polyclonal antibody. Positive FC detected in HeLa cells. Positive WB detected in Y79 cells, HEK-293 cells, mouse brain tissue. Observed molecular weight by Western-blot: 130 kDa, 60-80 kDa
  • Tested applications
    ELISA, WB, FC
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    hSorCS antibody; SORCS1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_052918). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    Y79 cells were subjected to SDS PAGE followed by western blot with Catalog No:115503(SORCS1 antibody) at dilution of 1:500

    Y79 cells were subjected to SDS PAGE followed by western blot with Catalog No:115503(SORCS1 antibody) at dilution of 1:500

    1X10^6 HeLa cells were stained with 0.2ug SORCS1 antibody (Catalog No:115503, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.

    1X10^6 HeLa cells were stained with 0.2ug SORCS1 antibody (Catalog No:115503, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.

  • Background
    SorCS1 is a 130 kDa type I transmembrane protein, belonging to Vps10p-domain (Vps10p-D) receptor family that comprises an N-terminal Vps10p-D, a leucine-rich domain, a single transmembrane domain, and a short cytoplasmic domain. SorCS1 is synthesized as a proprotein, which is converted to the mature receptor in late Golgi compartments by cleavage of the N-terminal propeptide. Alternative splicing of human SorCS1 results in four isoforms with different cytoplasmic domains and differential expression in tissues. This antibody was generated against the C-terminal region of human SorCS1 and recognizes various forms of SorCS1. Multiple bands around 100-130 kDa as well as 60-80 kDa have been detected in Y79 cells by western blot assay.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"