SOD3 antibody

Cat.#: 115494

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Product Information

  • Product Name
    SOD3 antibody
  • Documents
  • Description
    SOD3 Rabbit Polyclonal antibody. Positive IP detected in human placenta tissue. Positive WB detected in human heart tissue, human placenta tissue. Observed molecular weight by Western-blot: 25-33 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    EC SOD antibody; Extracellular superoxide dismutase antibody; SOD3 antibody; Superoxide Dismutase 3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of SOD3 recombinant protein (Accession Number: NM_003102). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:500-1:5000

  • Validations

    human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:115494(SOD3 antibody) at dilution of 1:1000

    human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:115494(SOD3 antibody) at dilution of 1:1000

    IP Result of anti-SOD3 (IP:Catalog No:115494, 4ug; Detection:Catalog No:115494 1:1000) with human placenta tissue lysate 2800ug.

    IP Result of anti-SOD3 (IP:Catalog No:115494, 4ug; Detection:Catalog No:115494 1:1000) with human placenta tissue lysate 2800ug.

  • Background
    SOD is located intracellular (SOD-1; cytosolic, SOD-2; mitochondrial matrix) and extracellular (SOD-3), and catalyzes the dismutation of superoxide anion to H2O2. SOD3, or EC-SOD, is the most recently characterized SOD, exists as a copper and zinc-containing tetramer, and is synthesized containing a signal peptide that directs this enzyme exclusively to extracellular spaces. SOD-3 is a Mn-containing tetrameric protein with a subunit Mr of 24-35 kDa. The activity of EC-SOD is dependent on its ability to form a tetramer of 135 kDa.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"