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Product Name
SNX3 antibody
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Description
SNX3 Rabbit Polyclonal antibody. Positive WB detected in COLO 320 cells, A549 cells, HeLa cells. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 16-20 kDa
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Tested applications
ELISA, WB, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Grd19 antibody; MCOPS8 antibody; Protein SDP3 antibody; SDP3 antibody; SNX3 antibody; sorting nexin 3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SNX3 recombinant protein (Accession Number: NM_003795). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IF: 1:10-1:100
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Validations
COLO 320 cells were subjected to SDS PAGE followed by western blot with Catalog No:115480(SNX3 antibody) at dilution of 1:500
Immunofluorescent analysis of HeLa cells using Catalog No:115480(SNX3 Antibody) at dilution of 1:25 and Alexa Fluor 594-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
SNX3 is a member of the sorting nexin family of proteins regulating membrane traffic. SNX3 regulates endosomal function through its PX (phox homology)-domain-mediated interaction with PtdIns(3)P (PMID: 11433298). It is a potential regulator of neurite formation and may play an important role in the development and function of the central nervous system (PMID: 19576982; 20817026).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"