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Product Name
SNRNP70 Polyclonal Antibody
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Description
Polyclonal antibody to SNRNP70
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Tested applications
WB, IHC
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Species reactivity
Human, Mouse, Rat
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Alternative names
SNRNP70 antibody; RNPU1Z antibody; RPU1 antibody; SNRP70 antibody; Snp1 antibody; U1-70K antibody; U170K antibody; U1AP antibody; U1RNP antibody; U1 small nuclear ribonucleoprotein 70 kDa antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SNRNP70 (NP_003080.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
IHC 1:50 - 1:100 -
Validations
Western blot - SNRNP70 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using SNRNP70 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit .Exposure time: 90s.
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat liver using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat testis using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat ovary using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat brain using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat spleen using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat heart using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat pancreas using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human tonsil using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human colon using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human colon carcinoma using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human breast cancer using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human stomach using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human uterus using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human uterine cancer using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse testis using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse spinal cord using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse brain using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse spleen using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse kidney using SNRNP70 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - SNRNP70 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse pancreas using SNRNP70 antibody at dilution of 1:100 (40x lens).
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Background
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA.; Isoform 3: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.; Isoform 4: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"